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Why prolong your misery by losing lots of cash on the slot machines? Go out like a high roller — hit the roulette table and 
put it all on one number, says Dr. Robert Hannum, a professor of risk analysis and gaming at University of Denver. “You’ll win the straight-up bet on a single number in roulette once every 38 times,” he says. So the odds offer a 35-to-one payout. Sounds a bit too rich? Then stretch out your play in R100 hits, you’ll still have a 12.5% chance of pocketing some cash.